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Neurogenic Bladder

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What is a neurogenic bladder?

The bladder has two main functions:

  • Storage of urine and then to
  • Empty the urine when it is full.

 
For this process to be successful, the nerves and the muscles of the urinary tract must work together. Nerves carry messages from the bladder to the brain and from the brain to the muscles of the bladder and sphincter .

The messages from brain centre tell the bladder muscle when to relax or contract.

In a neurogenic bladder, the nerves that are supposed to carry these messages to the bladder do not work properly so the bladder is not able to store or empty urine effectively.

Causes

In children, a neurogenic bladder may be related to a birth defect, or it may be acquired as the result of a different problem. The following are some of the most common causes of neurogenic bladder:

  • Spina bifida
  • Tethered spinal cord
  • Caudal regression
  • Transverse myelitis
  • Spinal cord trauma
  • Central nervous system tumors
  • Pelvic tumors
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Symptoms

Symptoms of neurogenic bladder may vary depending upon the cause and other associated conditions.

  • Urine leakage/dribbling/incontinence
  • Urine retention,
  • Recurrent fever,
  • Pain abdomen/flanks.
  • Weakness in lower limbs,
  • Swelling lower back
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Evaluation and diagnosis

Tests to confirm the diagnosis and extent of the condition include:

  • ULTRASOUND (KUB/Abdomen) to evaluate the anatomy of the kidneys and bladder, tumours retroperitoneum.
  • URODYNAMIC STUDY/ Video urodynamic study to evaluate how well your child’s bladder fills, stores urine and empties
  • MCU/Voiding cystourethrogram to evaluate for Vesicoureteral Reflux (VUR), bladder neck and urethral problems.
  • MRI of the spine to evaluate congenital anomalies ,tumours 0f spine and pelvic cavity and tethered spinal cord.
  • Blood investigations- CBC, KFT, Basic Metabolic work up and Cystatin-C

Treatment

Goals of treating Neurogenic bladder:

  • to preserve renal function,
  • To achieve social continence and promote positive self-esteem.

 
A team of pediatricians, nurses and psychologists, physiotherapist works with the family.

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Medical management

  • Clean intermittent catheterization (CIC)
  • Overnight catheter drainage
  • Prophylactic antibiotic therapy
  • Anticholinergic medications
  • Beta3 Agonist Medication

Surgical management

Surgery may be appropriate for patients who have changes to the kidneys, ureters or bladder on radiology imaging, issues with storing urine in the bladder, recurrent UTIs, or whose incontinence cannot be controlled through medical measures.

  • Vesicostomy
  • Bladder augmentation
  • Appendicovesicostomy (Mitrofanoff)
  • Malone antegrade colonic enema (MACE)
  • Cecostomy button
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