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Wilms Tumor

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Wilms Tumor

Wilms tumor, also called nephroblastoma, is a malignant (cancerous) tumor originating in the cells of the kidney. It is the most common type of renal (kidney) cancer and accounts for about 6 percent of all childhood cancers.

Most children with Wilms tumor can be cured of the disease.Approximately 5-10 percent of children with Wilms tumor have both kidneys involved.

Signs and symptoms

  • Abdominal swelling, often toward one side
  • Fever
  • Abdominal pain
  • High blood pressure (hypertension)
  • Large swollen veins across the abdomen
  • Blood in the urine (hematuria)
  • Loss of appetite, weight loss. fatigue
  • Frequent urinary tract infections
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Diagnosis of Wilms tumor

After taking a complete medical history and doing a physical examination of your child, the physician may also order the following tests to determine if the cancer has spread (metastasized):

  • Abdominal ultrasound,
  • Abdominal computerized tomography scan (CT or CAT scan),  for detailed cross-sectional images of the body, including the bones, muscles, fat and organs. It shows a mass in the kidneys and whether it has  spread outside the kidney capsule, lymph nodes, IVC to other organs such as the lungs.
  • Chest X-ray, This imaging test produces images of the heart, lungs and bones.
  • Magnetic resonance imaging (MRI).
  • Blood and urine tests including kidney and liver function.
  • Biopsy, A sample of tissue is removed and examined under a microscope; this helps confirm the diagnosis and aids in the treatment plan.

Treatment for Wilms tumor

Depending on the staging system and biopsy, the treatment may be:

  • Surgery-Radical nephrectomy, Partial nephrectomy, nephron-sparing surgery (NSS)
  • Chemotherapy-Neoadjuvant, Adjuvant.
  • Radiotherapy.
  • Immunotherapy.
  • PROTON THERAPY FOR WILMS TUMOR
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